Open-minded Americans will easily acclimate to Canada. The people are fantastic, the culture is similar, and it's quite like what the US might be if we all were a little nicer and a little more considerate.
But unless you already have a job lined up, it's reasonably difficult to make a permanent move and if you're of retirement age, even moreso. Canada has excellent health and eldercare policies, and they're not about to waste money on you if you haven't been contributing to its upkeep.
The easiest way to emigrate is to find a Canadian company in need of your specific skill -- or find a friendly Canadian to marry. Citizenship and Immigration Canada has some excellent resource guides, at least on the former. Maybe OKCupid for the latter?
Cost of Living
Canada's cost of living is pretty much on par with that in the United States. Find out more by clicking above.
It's not too different than in the US -- perhaps just a little cooler.
Read all you can before making any kind of decision.
Websites and forums to get a flavo(u)r of your possible new home.
The legal bits
Canadians are welcoming people -- but getting the proper permission to move can be daunting. Find out more here.